Mother's Hips Predict Daughter's Breast Cancer Risks

Oct 11, 2007
Scientists found out a strong link between the size and shape of woman's hips and her daughter's probability of developing breast cancer in future.

The research conducted by David J.P. Barker, M.D., Ph.D., and Kent Thornburg, Ph.D., of Oregon Health & Science University implies that the more voluptuous hips woman has - the more it will be a breast cancer risk to her daughter.

The level of sex hormone concentration contribute to the growth of hip bones and women having wider round hips have higher concentration of these hormones. The hormone profile is individual for every woman and remains through her reproductive period.

Researchers kept record of more than 6,000 women born in Helsinki from 1934 to 1944, having measured their pelvis bones during pregnancy. The findings showed that women had three times higher risks of breast cancer if their mother had wide hips and seven times higher risks if they happened to be a second or third child.

Also it was discovered that the wider was the distance between the wing-like structures of their hips the more chances were that daughters would develop breast cancer.

Scientists from the OHSU say that breast cancer is triggered by sex hormones during the first trimester of pregnancy when mother's sex hormones influence the development of fetal breast.

The wide round hips is an indicator of high concentrations of estradiol, resulting in chromosomal instability by breaking DNA strands and lead to breasts susceptible to cancer later in life.

During a study, women born in during 1934-1944 at either Helsinki University Central Hospital or City Maternity Hospital, Finland were registered for breast cancer and it was found that three hundred of them had had breast cancer.

The findings also showed that pubertal growth spurt of girls, which is an indicator of nutrition level, is strongly linked to the development of breast cancer in their daughters.

Healthy Life Spot